Rejuvenation & wrinkle removal is the reversal of aging and thus requires a different strategy, namely repair of the damage that is associated with aging or replacement of damaged tissue with new tissue.

Skin aging is noted by a decrease in volume and elasticity. As skin ages, it becomes thinner and more easily damaged. Intensifying this effect by decreasing the ability of skin to heal itself.

Skin wrinkles typically appear as a result of aging processes such as glycation, habitual sleeping positions, loss of body mass. Age wrinkling in the skin is promoted by habitual facial expressions, aging, sun damage, smoking, poor hydration, and various other factors.